Sinclair Method Studies
This article examines the scientific foundation behind TSM, drawing on nearly three decades of peer‑reviewed trials, neuroimaging research, and systematic reviews.

The National Health Service (NHS) bears a significant portion of the financial burden associated with alcohol misuse. Recent estimates indicate that alcohol-related harm costs the NHS approximately £4.91 billion annually, encompassing expenses related to hospital admissions, ambulance services, and treatments for alcohol dependency.
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